I have used Sunshine + Moonlight over fibre + 5G based networks and its worked pretty nicely before. This was over Tailscale and routed over a DERP relay (worse latency, more hops due to CG-NAT). As long as your host internet speeds has good uploads and usable latency as well as your server/desktop connected wired to your router over Ethernet then it usually works well. Does depend on your network but it does work (and pretty well, as long as everything is configured properly), but YMMV.
I have used Sunshine + Moonlight over fibre + 5G based networks and its worked pretty nicely before. This was over Tailscale and routed over a DERP relay (worse latency, more hops due to CG-NAT). As long as your host internet speeds has good uploads and usable latency as well as your server/desktop connected wired to your router over Ethernet then it usually works well. Does depend on your network but it does work (and pretty well, as long as everything is configured properly), but YMMV.